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Midostaurin

Synonyms

SourcesNames Used
GDSC1000Midostaurin
PharmacoGx Midostaurin

External IDs

DatabaseIdentifier
Smiles: CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Inchikey: BMGQWWVMWDBQGC-PZFYLCKJSA-N
Pubchem: 24202429

Annotated Targets

KIT, FLT3, PRKCG

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Midostaurin


Feature TypeStandardized
Nominal ANOVA
mRNA ACTN4 GDSC1000 pan-cancer AAC 0.21 1e-07
mRNA ELK3 GDSC1000 pan-cancer AAC 0.19 1e-07
mRNA CPA4 GDSC1000 pan-cancer AAC 0.19 1e-07
mRNA PLAU GDSC1000 pan-cancer AAC 0.22 2e-07
mRNA POU3F2 GDSC1000 pan-cancer AAC -0.2 2e-07
mRNA ZYX GDSC1000 pan-cancer AAC 0.19 2e-07
mRNA FLT3 GDSC1000 pan-cancer AAC 0.19 2e-07
mRNA GAS6 GDSC1000 pan-cancer AAC 0.21 2e-07
mRNA NECTIN2 GDSC1000 pan-cancer AAC 0.23 2e-07
mRNA MYL9 GDSC1000 pan-cancer AAC 0.19 2e-07
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