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Midostaurin

Synonyms

SourcesNames Used
GDSC1000Midostaurin
PharmacoGx Midostaurin

External IDs

DatabaseIdentifier
Smiles: CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Inchikey: BMGQWWVMWDBQGC-PZFYLCKJSA-N
Pubchem: 24202429

Annotated Targets

KIT, FLT3, PRKCG

FDA Approval Status

Approved
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Top molecular features associated with response to Midostaurin


Feature TypeStandardized
Nominal ANOVA
mRNA GCH1 GDSC1000 pan-cancer AAC -0.21 4e-08
mRNA ASPH GDSC1000 pan-cancer AAC 0.23 5e-08
mRNA SERPINE1 GDSC1000 pan-cancer AAC 0.22 5e-08
mRNA ERLIN1 GDSC1000 pan-cancer AAC 0.19 6e-08
mRNA SBK1 GDSC1000 pan-cancer AAC -0.22 6e-08
mRNA VCL GDSC1000 pan-cancer AAC 0.21 7e-08
mRNA DPYSL5 GDSC1000 pan-cancer AAC -0.21 7e-08
mRNA GNAI2 GDSC1000 pan-cancer AAC 0.22 7e-08
mRNA MREG GDSC1000 pan-cancer AAC -0.2 7e-08
mRNA FBN1 GDSC1000 pan-cancer AAC 0.21 7e-08
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