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Doxorubicin

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMDoxorubicin
gCSI, CTRPv2doxorubicin
PharmacoGx Doxorubicin

External IDs

DatabaseIdentifier
Smiles: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
Inchikey: MWWSFMDVAYGXBV-FGBJBKNOSA-N
Pubchem: 32874

Annotated Targets

TOP2A

FDA Approval Status

Approved
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Top molecular features associated with response to Doxorubicin


Feature TypeStandardized
Nominal ANOVA
mRNA RPAIN gCSI pan-cancer AAC 0.34 9e-12
mRNA BCL2L1 CTRPv2 pan-cancer AAC -0.21 1e-11
mRNA NUP88 gCSI pan-cancer AAC 0.33 2e-11
mRNA POLR1E gCSI pan-cancer AAC 0.33 2e-11
mRNA RCOR2 CTRPv2 pan-cancer AAC 0.21 2e-11
mRNA SFPQ CTRPv2 pan-cancer AAC 0.21 2e-11
mRNA MYOF CTRPv2 pan-cancer AAC -0.23 3e-11
mRNA MCFD2 CTRPv2 pan-cancer AAC -0.21 3e-11
mRNA CPSF6 CTRPv2 pan-cancer AAC 0.22 4e-11
mRNA HNRNPC gCSI pan-cancer AAC 0.33 4e-11
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