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AG-014699

AG-014699

Synonyms

Sources	Names Used
GDSC1000	AG-014699
PharmacoGx	AG-014699

External IDs

Database	Identifier
Smiles:	CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(=CC(=C34)N2)F.OP(=O)(O)O
Inchikey:	FCCGJTKEKXUBFZ-UHFFFAOYSA-N
Pubchem:	9931953

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AG-014699

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RPLP1	GDSC1000	pan-cancer	AAC	0.13	0.0002
mRNA	KATNBL1	GDSC1000	pan-cancer	AAC	0.13	0.0002
mRNA	LCE2B	GDSC1000	pan-cancer	AAC	-0.13	0.0002
mRNA	NPM3	GDSC1000	pan-cancer	AAC	0.13	0.0002
mRNA	SYP	GDSC1000	pan-cancer	AAC	-0.13	0.0002
mRNA	HIF3A	GDSC1000	pan-cancer	AAC	-0.13	0.0002
mRNA	SLC6A6	GDSC1000	pan-cancer	AAC	-0.13	0.0002
mRNA	CARD8	GDSC1000	pan-cancer	AAC	0.17	0.0002
mRNA	LCE3D	GDSC1000	pan-cancer	AAC	-0.12	0.0002
mRNA	MAP2K5	GDSC1000	pan-cancer	AAC	0.13	0.0002

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