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Roscovitine

Roscovitine

Synonyms

Sources	Names Used
GDSC1000	Roscovitine
FIMM	Seliciclib
PharmacoGx	Roscovitine

External IDs

Database	Identifier
Smiles:	CCC(CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C
Inchikey:	BTIHMVBBUGXLCJ-OAHLLOKOSA-N
Pubchem:	160355

Annotated Targets

CDK2, CDK9

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to Roscovitine

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ADAM7	FIMM	pan-cancer	AAC	0.35	0.03
mRNA	ADAP1	FIMM	pan-cancer	AAC	-0.33	0.05
mRNA	ADAR	GDSC1000	pan-cancer	AAC	0.18	0.001
mRNA	ADD1	FIMM	pan-cancer	AAC	0.33	0.05
mRNA	ADD3	GDSC1000	pan-cancer	AAC	-0.11	0.05
mRNA	ADGRL3	GDSC1000	pan-cancer	AAC	-0.14	0.01
mRNA	ADK	GDSC1000	pan-cancer	AAC	-0.11	0.04
mRNA	ADNP2	GDSC1000	pan-cancer	AAC	-0.15	0.005
mRNA	ADPRM	GDSC1000	pan-cancer	AAC	0.12	0.03
mRNA	ADRA1A	FIMM	pan-cancer	AAC	0.37	0.03

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