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Roscovitine

Synonyms

SourcesNames Used
GDSC1000Roscovitine
FIMMSeliciclib
PharmacoGx Roscovitine

External IDs

DatabaseIdentifier
Smiles: CCC(CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C
Inchikey: BTIHMVBBUGXLCJ-OAHLLOKOSA-N
Pubchem: 160355

Annotated Targets

CDK2, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to Roscovitine


Feature TypeStandardized
Nominal ANOVA
mRNA INTS7 FIMM pan-cancer AAC -0.46 0.05
mRNA ZNF396 GDSC1000 pan-cancer AAC -0.1 0.05
mRNA IDH1 FIMM pan-cancer AAC -0.33 0.05
mRNA SFRP5 GDSC1000 pan-cancer AAC -0.1 0.05
mRNA CENPN FIMM pan-cancer AAC -0.35 0.05
mRNA TEX10 GDSC1000 pan-cancer AAC -0.11 0.05
mRNA RAB4A FIMM pan-cancer AAC -0.32 0.05
mRNA CSPG4 GDSC1000 pan-cancer AAC 0.13 0.05
mRNA MSH2 GDSC1000 pan-cancer AAC -0.11 0.05
mRNA DNAJB9 GDSC1000 pan-cancer AAC 0.1 0.05
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