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Roscovitine

Synonyms

SourcesNames Used
GDSC1000Roscovitine
FIMMSeliciclib
PharmacoGx Roscovitine

External IDs

DatabaseIdentifier
Smiles: CCC(CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C
Inchikey: BTIHMVBBUGXLCJ-OAHLLOKOSA-N
Pubchem: 160355

Annotated Targets

CDK2, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to Roscovitine


Feature TypeStandardized
Nominal ANOVA
mRNA RHOC FIMM pan-cancer AAC 0.43 0.05
mRNA WNK3 GDSC1000 pan-cancer AAC -0.13 0.05
mRNA KIAA0895L GDSC1000 pan-cancer AAC -0.11 0.05
mRNA FOXC1 GDSC1000 pan-cancer AAC -0.12 0.05
mRNA TNFSF9 FIMM pan-cancer AAC 0.35 0.05
mRNA RRAGA GDSC1000 pan-cancer AAC 0.11 0.05
mRNA ZNF708 GDSC1000 pan-cancer AAC -0.13 0.05
mRNA CASC1 GDSC1000 pan-cancer AAC 0.11 0.05
mRNA PAQR4 GDSC1000 pan-cancer AAC -0.11 0.05
mRNA TTR GDSC1000 pan-cancer AAC -0.11 0.05
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