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Roscovitine

Synonyms

SourcesNames Used
GDSC1000Roscovitine
FIMMSeliciclib
PharmacoGx Roscovitine

External IDs

DatabaseIdentifier
Smiles: CCC(CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C
Inchikey: BTIHMVBBUGXLCJ-OAHLLOKOSA-N
Pubchem: 160355

Annotated Targets

CDK2, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to Roscovitine


Feature TypeStandardized
Nominal ANOVA
mRNA PPP1CC GDSC1000 pan-cancer AAC -0.12 0.04
mRNA SOX15 FIMM pan-cancer AAC 0.34 0.04
mRNA ZMIZ2 FIMM pan-cancer AAC 0.35 0.04
mRNA AHCYL2 GDSC1000 pan-cancer AAC 0.11 0.04
mRNA ZBTB16 FIMM pan-cancer AAC 0.35 0.04
mRNA UGT2B7 GDSC1000 pan-cancer AAC 0.13 0.04
mRNA CFAP20 GDSC1000 pan-cancer AAC -0.11 0.04
mRNA DYNC1H1 FIMM pan-cancer AAC 0.37 0.04
mRNA SAT1 FIMM pan-cancer AAC -0.36 0.04
mRNA PRR16 FIMM pan-cancer AAC 0.33 0.04
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