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Roscovitine

Synonyms

SourcesNames Used
GDSC1000Roscovitine
FIMMSeliciclib
PharmacoGx Roscovitine

External IDs

DatabaseIdentifier
Smiles: CCC(CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C
Inchikey: BTIHMVBBUGXLCJ-OAHLLOKOSA-N
Pubchem: 160355

Annotated Targets

CDK2, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to Roscovitine


Feature TypeStandardized
Nominal ANOVA
mRNA DOCK8 GDSC1000 pan-cancer AAC -0.16 0.05
mRNA PSMB3 FIMM pan-cancer AAC -0.34 0.05
mRNA TBCA GDSC1000 pan-cancer AAC -0.11 0.05
mRNA CYP3A5 GDSC1000 pan-cancer AAC 0.13 0.05
mRNA ALDH6A1 FIMM pan-cancer AAC -0.33 0.05
mRNA PSPN FIMM pan-cancer AAC 0.32 0.05
mRNA ARHGEF28 FIMM pan-cancer AAC 0.46 0.05
mRNA IL25 FIMM pan-cancer AAC 0.34 0.05
mRNA TMEM70 GDSC1000 pan-cancer AAC -0.11 0.05
mRNA SRSF9 FIMM pan-cancer AAC -0.34 0.05
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