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Roscovitine

Synonyms

SourcesNames Used
GDSC1000Roscovitine
FIMMSeliciclib
PharmacoGx Roscovitine

External IDs

DatabaseIdentifier
Smiles: CCC(CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C
Inchikey: BTIHMVBBUGXLCJ-OAHLLOKOSA-N
Pubchem: 160355

Annotated Targets

CDK2, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to Roscovitine


Feature TypeStandardized
Nominal ANOVA
mRNA CEACAM6 GDSC1000 pan-cancer AAC 0.12 0.04
mRNA VSX1 GDSC1000 pan-cancer AAC 0.11 0.04
mRNA LDOC1L GDSC1000 pan-cancer AAC -0.14 0.04
mRNA TRPC3 FIMM pan-cancer AAC 0.33 0.04
mRNA PPP2R2B FIMM pan-cancer AAC 0.32 0.04
mRNA ETS1 FIMM pan-cancer AAC 0.35 0.04
mRNA MIER2 FIMM pan-cancer AAC 0.4 0.04
mRNA DCHS1 FIMM pan-cancer AAC 0.36 0.04
mRNA IL36G GDSC1000 pan-cancer AAC -0.11 0.04
mRNA HMGB2 GDSC1000 pan-cancer AAC -0.12 0.04
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