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Roscovitine

Synonyms

SourcesNames Used
GDSC1000Roscovitine
FIMMSeliciclib
PharmacoGx Roscovitine

External IDs

DatabaseIdentifier
Smiles: CCC(CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C
Inchikey: BTIHMVBBUGXLCJ-OAHLLOKOSA-N
Pubchem: 160355

Annotated Targets

CDK2, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to Roscovitine


Feature TypeStandardized
Nominal ANOVA
mRNA HIST1H3F FIMM pan-cancer AAC -0.38 0.04
mRNA SEC61G GDSC1000 pan-cancer AAC 0.1 0.04
mRNA DNALI1 GDSC1000 pan-cancer AAC -0.12 0.04
mRNA FAM24A GDSC1000 pan-cancer AAC 0.11 0.04
mRNA XKR4 GDSC1000 pan-cancer AAC -0.12 0.04
mRNA HSPA14 GDSC1000 pan-cancer AAC -0.11 0.04
mRNA SERPINE2 GDSC1000 pan-cancer AAC 0.13 0.04
mRNA TENM4 FIMM pan-cancer AAC 0.39 0.04
mRNA PCGF3 FIMM pan-cancer AAC 0.33 0.04
mRNA HNRNPA3 GDSC1000 pan-cancer AAC -0.12 0.04
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