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AZD6482

Synonyms

SourcesNames Used
GDSC1000, CTRPv2AZD6482
PharmacoGx AZD6482

External IDs

DatabaseIdentifier
Smiles: CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3C(=O)O)N4CCOCC4
Inchikey: IRTDIKMSKMREGO-OAHLLOKOSA-N
Pubchem: 44137675

Annotated Targets

PIK3CD, PIK3CA, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD6482


Feature TypeStandardized
Nominal ANOVA
mRNA ZC3H12D CTRPv2 pan-cancer AAC 0.3 6e-13
mRNA TNFRSF13C CTRPv2 pan-cancer AAC 0.27 5e-12
mRNA NCF1 CTRPv2 pan-cancer AAC 0.27 6e-12
mRNA CD79B CTRPv2 pan-cancer AAC 0.25 7e-11
mRNA BLK CTRPv2 pan-cancer AAC 0.26 2e-10
mRNA IRF8 CTRPv2 pan-cancer AAC 0.26 2e-10
mRNA CD22 CTRPv2 pan-cancer AAC 0.23 1e-09
mRNA FFAR1 CTRPv2 pan-cancer AAC 0.22 2e-09
mRNA MKL1 GDSC1000 pan-cancer AAC 0.21 2e-09
mRNA NFE2 CTRPv2 pan-cancer AAC -0.22 3e-09
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