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AZD6244

Synonyms

SourcesNames Used
CCLE, GRAY, UHNBreastAZD6244
GDSC1000, CTRPv2selumetinib
FIMMSelumetinib
PharmacoGx AZD6244

External IDs

DatabaseIdentifier
Smiles: CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
Inchikey: CYOHGALHFOKKQC-UHFFFAOYSA-N
Pubchem: 10127622

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD6244


Feature TypeStandardized
Nominal ANOVA
mRNA SIRPB2 CCLE pan-cancer AAC 0.25 5e-09
mRNA KCNE3 CCLE pan-cancer AAC 0.28 5e-09
mRNA ETV5 CCLE pan-cancer AAC 0.28 6e-09
mRNA CD300LF CCLE pan-cancer AAC 0.25 6e-09
mRNA CLEC12A CCLE pan-cancer AAC 0.25 6e-09
mRNA RREB1 CCLE pan-cancer AAC 0.27 7e-09
mRNA CLEC5A CCLE pan-cancer AAC 0.24 8e-09
mRNA MZB1 CCLE pan-cancer AAC -0.35 9e-09
mRNA EMILIN2 CCLE pan-cancer AAC 0.24 2e-08
mRNA MANSC1 CCLE pan-cancer AAC 0.3 2e-08
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