1. Home/
  2. Compounds/
  3. AZD6244

AZD6244

Synonyms

SourcesNames Used
CCLE, GRAY, UHNBreastAZD6244
GDSC1000, CTRPv2selumetinib
FIMMSelumetinib
PharmacoGx AZD6244

External IDs

DatabaseIdentifier
Smiles: CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
Inchikey: CYOHGALHFOKKQC-UHFFFAOYSA-N
Pubchem: 10127622

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to AZD6244


Feature TypeStandardized
Nominal ANOVA
mRNA WDR76 CTRPv2 pan-cancer AAC -0.25 6e-11
mRNA LYST CTRPv2 pan-cancer AAC 0.25 6e-11
mRNA SLC35D2 CTRPv2 pan-cancer AAC 0.28 6e-11
mRNA NPAS2 CCLE pan-cancer AAC 0.3 7e-11
mRNA GKAP1 CTRPv2 pan-cancer AAC -0.24 9e-11
mRNA C16orf87 CTRPv2 pan-cancer AAC -0.24 1e-10
mRNA SPECC1L-ADORA2A CTRPv2 pan-cancer AAC -0.24 1e-10
mRNA GPR35 CTRPv2 pan-cancer AAC 0.25 2e-10
mRNA PRPS1 CTRPv2 pan-cancer AAC -0.23 2e-10
mRNA MGST2 CTRPv2 pan-cancer AAC 0.22 2e-10
Download CSV