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SB590885

SB590885

Synonyms

Sources	Names Used
GDSC1000	SB590885
PharmacoGx	SB590885

External IDs

Database	Identifier
Smiles:	CN(C)CCOC1=CC=C(C=C1)C2=NC(=C3C=CC4=C(CCC4=C3)N=O)C(=C5C=CNC=C5)N2
Inchikey:	DPCXEUSDRQOOGZ-QLYXXIJNSA-N
Pubchem:	11316960

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB590885

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	P2RX4	GDSC1000	pan-cancer	AAC	0.079	0.01
mRNA	KIAA1024	GDSC1000	pan-cancer	AAC	0.08	0.01
mRNA	ATP1A1	GDSC1000	pan-cancer	AAC	0.091	0.01
mRNA	ATP6V0A2	GDSC1000	pan-cancer	AAC	-0.098	0.01
mRNA	TMEM177	GDSC1000	pan-cancer	AAC	0.081	0.01
mRNA	COX5A	GDSC1000	pan-cancer	AAC	0.087	0.01
mRNA	OR52K1	GDSC1000	pan-cancer	AAC	0.076	0.01
mRNA	PAWR	GDSC1000	pan-cancer	AAC	-0.093	0.01
mRNA	PFN3	GDSC1000	pan-cancer	AAC	-0.078	0.01
mRNA	PLXDC2	GDSC1000	pan-cancer	AAC	-0.083	0.01

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