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SB590885

SB590885

Synonyms

Sources	Names Used
GDSC1000	SB590885
PharmacoGx	SB590885

External IDs

Database	Identifier
Smiles:	CN(C)CCOC1=CC=C(C=C1)C2=NC(=C3C=CC4=C(CCC4=C3)N=O)C(=C5C=CNC=C5)N2
Inchikey:	DPCXEUSDRQOOGZ-QLYXXIJNSA-N
Pubchem:	11316960

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB590885

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CDC37L1	GDSC1000	pan-cancer	AAC	-0.081	0.01
mRNA	TSR2	GDSC1000	pan-cancer	AAC	-0.08	0.01
mRNA	AFDN	GDSC1000	pan-cancer	AAC	-0.085	0.01
mRNA	LMBR1L	GDSC1000	pan-cancer	AAC	0.085	0.01
mRNA	TCF7	GDSC1000	pan-cancer	AAC	0.08	0.01
mRNA	HS1BP3	GDSC1000	pan-cancer	AAC	0.085	0.01
mRNA	ST3GAL6	GDSC1000	pan-cancer	AAC	0.095	0.01
mRNA	BEX1	GDSC1000	pan-cancer	AAC	-0.093	0.01
mRNA	LRP5	GDSC1000	pan-cancer	AAC	0.088	0.01
mRNA	TGFBR2	GDSC1000	pan-cancer	AAC	0.087	0.01

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