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SB590885

SB590885

Synonyms

Sources	Names Used
GDSC1000	SB590885
PharmacoGx	SB590885

External IDs

Database	Identifier
Smiles:	CN(C)CCOC1=CC=C(C=C1)C2=NC(=C3C=CC4=C(CCC4=C3)N=O)C(=C5C=CNC=C5)N2
Inchikey:	DPCXEUSDRQOOGZ-QLYXXIJNSA-N
Pubchem:	11316960

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB590885

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CHST11	GDSC1000	pan-cancer	AAC	0.14	8e-05
mRNA	DCAF12L2	GDSC1000	pan-cancer	AAC	-0.13	8e-05
mRNA	SLC24A1	GDSC1000	pan-cancer	AAC	0.12	8e-05
mRNA	CTSK	GDSC1000	pan-cancer	AAC	0.14	8e-05
mRNA	NRP2	GDSC1000	pan-cancer	AAC	0.14	8e-05
mRNA	CASP8	GDSC1000	pan-cancer	AAC	0.14	9e-05
mRNA	DNASE2B	GDSC1000	pan-cancer	AAC	0.12	9e-05
mRNA	CYP17A1	GDSC1000	pan-cancer	AAC	0.12	9e-05
mRNA	PLA2G2A	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	GLUD2	GDSC1000	pan-cancer	AAC	0.14	0.0001

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