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SB590885

SB590885

Synonyms

Sources	Names Used
GDSC1000	SB590885
PharmacoGx	SB590885

External IDs

Database	Identifier
Smiles:	CN(C)CCOC1=CC=C(C=C1)C2=NC(=C3C=CC4=C(CCC4=C3)N=O)C(=C5C=CNC=C5)N2
Inchikey:	DPCXEUSDRQOOGZ-QLYXXIJNSA-N
Pubchem:	11316960

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB590885

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CXCL1	GDSC1000	pan-cancer	AAC	0.081	0.02
mRNA	PLEKHD1	GDSC1000	pan-cancer	AAC	0.071	0.02
mRNA	PDIA5	GDSC1000	pan-cancer	AAC	0.075	0.02
mRNA	MKX	GDSC1000	pan-cancer	AAC	-0.073	0.02
mRNA	OR4S1	GDSC1000	pan-cancer	AAC	-0.072	0.02
mRNA	KHDC3L	GDSC1000	pan-cancer	AAC	-0.071	0.02
mRNA	SEC63	GDSC1000	pan-cancer	AAC	-0.073	0.02
mRNA	POLE3	GDSC1000	pan-cancer	AAC	-0.076	0.02
mRNA	DNASE1	GDSC1000	pan-cancer	AAC	0.073	0.02
mRNA	MGAT1	GDSC1000	pan-cancer	AAC	0.076	0.02

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