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SB590885

SB590885

Synonyms

Sources	Names Used
GDSC1000	SB590885
PharmacoGx	SB590885

External IDs

Database	Identifier
Smiles:	CN(C)CCOC1=CC=C(C=C1)C2=NC(=C3C=CC4=C(CCC4=C3)N=O)C(=C5C=CNC=C5)N2
Inchikey:	DPCXEUSDRQOOGZ-QLYXXIJNSA-N
Pubchem:	11316960

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB590885

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	VPS45	GDSC1000	pan-cancer	AAC	-0.084	0.01
mRNA	TRNP1	GDSC1000	pan-cancer	AAC	0.095	0.01
mRNA	CEP350	GDSC1000	pan-cancer	AAC	-0.09	0.01
mRNA	HEYL	GDSC1000	pan-cancer	AAC	-0.08	0.01
mRNA	LAMA1	GDSC1000	pan-cancer	AAC	0.086	0.01
mRNA	FAM89A	GDSC1000	pan-cancer	AAC	0.085	0.01
mRNA	SORBS1	GDSC1000	pan-cancer	AAC	0.084	0.01
mRNA	KIF13B	GDSC1000	pan-cancer	AAC	0.082	0.01
mRNA	SPR	GDSC1000	pan-cancer	AAC	0.11	0.01
mRNA	TMEM50B	GDSC1000	pan-cancer	AAC	0.081	0.01

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