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SB590885

SB590885

Synonyms

Sources	Names Used
GDSC1000	SB590885
PharmacoGx	SB590885

External IDs

Database	Identifier
Smiles:	CN(C)CCOC1=CC=C(C=C1)C2=NC(=C3C=CC4=C(CCC4=C3)N=O)C(=C5C=CNC=C5)N2
Inchikey:	DPCXEUSDRQOOGZ-QLYXXIJNSA-N
Pubchem:	11316960

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB590885

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CDK2	GDSC1000	pan-cancer	AAC	0.1	0.003
mRNA	MUC7	GDSC1000	pan-cancer	AAC	0.095	0.003
mRNA	CCDC134	GDSC1000	pan-cancer	AAC	0.095	0.003
mRNA	TMEM51	GDSC1000	pan-cancer	AAC	0.13	0.003
mRNA	SULT1C2	GDSC1000	pan-cancer	AAC	0.1	0.003
mRNA	ISG20	GDSC1000	pan-cancer	AAC	0.1	0.003
mRNA	HMGA2	GDSC1000	pan-cancer	AAC	0.1	0.003
mRNA	NEFM	GDSC1000	pan-cancer	AAC	-0.11	0.003
mRNA	PPM1N	GDSC1000	pan-cancer	AAC	0.095	0.003
mRNA	SLC39A12	GDSC1000	pan-cancer	AAC	0.094	0.003

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