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SB590885

SB590885

Synonyms

Sources	Names Used
GDSC1000	SB590885
PharmacoGx	SB590885

External IDs

Database	Identifier
Smiles:	CN(C)CCOC1=CC=C(C=C1)C2=NC(=C3C=CC4=C(CCC4=C3)N=O)C(=C5C=CNC=C5)N2
Inchikey:	DPCXEUSDRQOOGZ-QLYXXIJNSA-N
Pubchem:	11316960

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB590885

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ADAMTSL1	GDSC1000	pan-cancer	AAC	0.062	0.06
mRNA	CD5	GDSC1000	pan-cancer	AAC	0.061	0.06
mRNA	PPP1R12B	GDSC1000	pan-cancer	AAC	0.063	0.06
mRNA	BBC3	GDSC1000	pan-cancer	AAC	0.065	0.06
mRNA	LUZP1	GDSC1000	pan-cancer	AAC	0.067	0.06
mRNA	METTL2B	GDSC1000	pan-cancer	AAC	0.062	0.06
mRNA	CABP2	GDSC1000	pan-cancer	AAC	-0.061	0.06
mRNA	GSTM3	GDSC1000	pan-cancer	AAC	-0.067	0.06
mRNA	SCN5A	GDSC1000	pan-cancer	AAC	-0.064	0.06
mRNA	PTMA	GDSC1000	pan-cancer	AAC	-0.063	0.06

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