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PD-0325901

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0325901
gCSIpd0325901
PharmacoGx PD-0325901

External IDs

DatabaseIdentifier
Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
Inchikey: SUDAHWBOROXANE-SECBINFHSA-N
Pubchem: 9826528

Annotated Targets

MAP2K1, MAP2K2

FDA Approval Status

Not Approved
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Top molecular features associated with response to PD-0325901


Feature TypeStandardized
Nominal ANOVA
mRNA GNPDA1 gCSI pan-cancer AAC 0.25 7e-06
mRNA TMBIM6 GDSC1000 pan-cancer AAC 0.15 7e-06
mRNA CARMIL3 GDSC1000 pan-cancer AAC -0.15 7e-06
mRNA AICDA CCLE pan-cancer AAC -0.2 7e-06
mRNA PPP1R17 gCSI pan-cancer AAC -0.22 7e-06
mRNA NADSYN1 GDSC1000 pan-cancer AAC 0.16 7e-06
mRNA SYN1 GDSC1000 pan-cancer AAC -0.15 7e-06
mRNA HIST1H3F GDSC1000 pan-cancer AAC -0.16 7e-06
mRNA RHOG GDSC1000 pan-cancer AAC 0.18 7e-06
mRNA APOBR CCLE pan-cancer AAC 0.21 7e-06
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