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XMD8-85

XMD8-85

Synonyms

Sources	Names Used
GDSC1000	XMD8-85
PharmacoGx	XMD8-85

External IDs

Database	Identifier
Smiles:	COc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccccc3N(C)c2n1)N1CCN(C)CC1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XMD8-85

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	IL12RB2	GDSC1000	pan-cancer	AAC	0.18	0.0004
mRNA	CORO6	GDSC1000	pan-cancer	AAC	0.18	0.0004
mRNA	UBA7	GDSC1000	pan-cancer	AAC	0.21	0.0004
mRNA	ECM1	GDSC1000	pan-cancer	AAC	0.2	0.0004
mRNA	NARFL	GDSC1000	pan-cancer	AAC	0.19	0.0004
mRNA	THBS2	GDSC1000	pan-cancer	AAC	0.21	0.0005
mRNA	COL1A2	GDSC1000	pan-cancer	AAC	0.22	0.0005
mRNA	FIG4	GDSC1000	pan-cancer	AAC	-0.17	0.0005
mRNA	SSPN	GDSC1000	pan-cancer	AAC	0.21	0.0005
mRNA	CYS1	GDSC1000	pan-cancer	AAC	0.17	0.0005

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