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XMD8-85

XMD8-85

Synonyms

Sources	Names Used
GDSC1000	XMD8-85
PharmacoGx	XMD8-85

External IDs

Database	Identifier
Smiles:	COc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccccc3N(C)c2n1)N1CCN(C)CC1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XMD8-85

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	DEPDC5	GDSC1000	pan-cancer	AAC	0.1	0.08
mRNA	MSLNL	GDSC1000	pan-cancer	AAC	0.088	0.08
mRNA	POLE2	GDSC1000	pan-cancer	AAC	-0.097	0.08
mRNA	FN1	GDSC1000	pan-cancer	AAC	0.12	0.08
mRNA	SPDL1	GDSC1000	pan-cancer	AAC	-0.094	0.08
mRNA	SEP15	GDSC1000	pan-cancer	AAC	0.094	0.08
mRNA	DMRTA2	GDSC1000	pan-cancer	AAC	0.1	0.08
mRNA	SKIV2L2	GDSC1000	pan-cancer	AAC	-0.096	0.08
mRNA	SOHLH2	GDSC1000	pan-cancer	AAC	-0.087	0.08
mRNA	CREG1	GDSC1000	pan-cancer	AAC	0.096	0.08

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