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XMD8-85

XMD8-85

Synonyms

Sources	Names Used
GDSC1000	XMD8-85
PharmacoGx	XMD8-85

External IDs

Database	Identifier
Smiles:	COc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccccc3N(C)c2n1)N1CCN(C)CC1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XMD8-85

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	AGXT	GDSC1000	pan-cancer	AAC	0.1	0.05
mRNA	PDE6G	GDSC1000	pan-cancer	AAC	0.1	0.05
mRNA	FIBIN	GDSC1000	pan-cancer	AAC	0.11	0.05
mRNA	SESN1	GDSC1000	pan-cancer	AAC	-0.1	0.05
mRNA	CDK9	GDSC1000	pan-cancer	AAC	0.1	0.05
mRNA	PPP1R3G	GDSC1000	pan-cancer	AAC	0.098	0.05
mRNA	YTHDC1	GDSC1000	pan-cancer	AAC	0.11	0.05
mRNA	MYBBP1A	GDSC1000	pan-cancer	AAC	0.099	0.05
mRNA	LGALS14	GDSC1000	pan-cancer	AAC	-0.096	0.05
mRNA	BTNL8	GDSC1000	pan-cancer	AAC	-0.097	0.05

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