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XMD8-85

XMD8-85

Synonyms

Sources	Names Used
GDSC1000	XMD8-85
PharmacoGx	XMD8-85

External IDs

Database	Identifier
Smiles:	COc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccccc3N(C)c2n1)N1CCN(C)CC1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XMD8-85

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MAP4K5	GDSC1000	pan-cancer	AAC	-0.12	0.03
mRNA	ZNF862	GDSC1000	pan-cancer	AAC	0.11	0.03
mRNA	FBLIM1	GDSC1000	pan-cancer	AAC	0.15	0.03
mRNA	EN2	GDSC1000	pan-cancer	AAC	0.12	0.03
mRNA	BCL7B	GDSC1000	pan-cancer	AAC	0.12	0.03
mRNA	PPA1	GDSC1000	pan-cancer	AAC	-0.13	0.03
mRNA	ISOC2	GDSC1000	pan-cancer	AAC	0.11	0.03
mRNA	REP15	GDSC1000	pan-cancer	AAC	0.12	0.03
mRNA	ROS1	GDSC1000	pan-cancer	AAC	0.11	0.03
mRNA	PLA2G2E	GDSC1000	pan-cancer	AAC	0.11	0.03

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