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XMD8-85

XMD8-85

Synonyms

Sources	Names Used
GDSC1000	XMD8-85
PharmacoGx	XMD8-85

External IDs

Database	Identifier
Smiles:	COc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccccc3N(C)c2n1)N1CCN(C)CC1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XMD8-85

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PLXNA4	GDSC1000	pan-cancer	AAC	0.15	0.005
mRNA	BCL2A1	GDSC1000	pan-cancer	AAC	-0.16	0.005
mRNA	CD81	GDSC1000	pan-cancer	AAC	0.14	0.005
mRNA	CDH11	GDSC1000	pan-cancer	AAC	0.18	0.005
mRNA	NT5C	GDSC1000	pan-cancer	AAC	-0.14	0.005
mRNA	CALD1	GDSC1000	pan-cancer	AAC	0.23	0.005
mRNA	PDE4A	GDSC1000	pan-cancer	AAC	0.16	0.005
mRNA	HSPG2	GDSC1000	pan-cancer	AAC	0.17	0.005
mRNA	MBIP	GDSC1000	pan-cancer	AAC	-0.16	0.005
mRNA	C4orf3	GDSC1000	pan-cancer	AAC	0.14	0.006

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