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XMD8-85

XMD8-85

Synonyms

Sources	Names Used
GDSC1000	XMD8-85
PharmacoGx	XMD8-85

External IDs

Database	Identifier
Smiles:	COc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccccc3N(C)c2n1)N1CCN(C)CC1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XMD8-85

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	THBS1	GDSC1000	pan-cancer	AAC	0.23	0.004
mRNA	PEX6	GDSC1000	pan-cancer	AAC	0.14	0.004
mRNA	EPHX1	GDSC1000	pan-cancer	AAC	0.17	0.004
mRNA	CHST15	GDSC1000	pan-cancer	AAC	0.15	0.004
mRNA	CPSF3	GDSC1000	pan-cancer	AAC	-0.17	0.004
mRNA	HSPB6	GDSC1000	pan-cancer	AAC	0.15	0.004
mRNA	SH2D4B	GDSC1000	pan-cancer	AAC	0.14	0.004
mRNA	CCDC190	GDSC1000	pan-cancer	AAC	0.15	0.004
mRNA	ADAM10	GDSC1000	pan-cancer	AAC	0.16	0.004
mRNA	PGS1	GDSC1000	pan-cancer	AAC	-0.15	0.004

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