PharmacoDB

Sources

Names Used

GDC0941

gdc0941

Pictilisib

GDC-0941

PharmacoGx

GDC-0941

Database	Identifier
Smiles:	CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
Inchikey:	LHNIIDJUOCFXAP-UHFFFAOYSA-N
Pubchem:	17755052

Database

Identifier

Smiles:

CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6

Inchikey:

LHNIIDJUOCFXAP-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to GDC-0941

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ACD	gCSI	pan-cancer	AAC	-0.22	0.0003
mRNA	ACOT11	gCSI	pan-cancer	AAC	-0.23	0.0008
mRNA	ACOT6	CTRPv2	pan-cancer	AAC	0.13	0.0009
mRNA	ACOT6	GDSC1000	pan-cancer	AAC	0.11	0.002
mRNA	ACOT7	GDSC1000	pan-cancer	AAC	-0.1	0.002
mRNA	ACSL4	CTRPv2	pan-cancer	AAC	-0.12	0.001
mRNA	ACSM3	CTRPv2	pan-cancer	AAC	-0.11	0.002
mRNA	ACSS2	gCSI	pan-cancer	AAC	-0.19	0.002
mRNA	ACTN1	CTRPv2	pan-cancer	AAC	-0.12	0.005
mRNA	ACTN3	CTRPv2	pan-cancer	AAC	0.1	0.005