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RO-3306

RO-3306

Synonyms

Sources	Names Used
GDSC1000	RO-3306
PharmacoGx	RO-3306

External IDs

Database	Identifier
Smiles:	C1=CC2=C(C=CC(=C2)C=C3C(=O)N=C(S3)NCC4=CC=CS4)N=C1
Inchikey:	XOLMRFUGOINFDQ-UHFFFAOYSA-N
Pubchem:	71433937

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to RO-3306

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SERPINH1	GDSC1000	pan-cancer	AAC	0.22	2e-07
mRNA	IER3	GDSC1000	pan-cancer	AAC	0.22	3e-07
mRNA	BAG3	GDSC1000	pan-cancer	AAC	0.22	1e-07
mRNA	GPX8	GDSC1000	pan-cancer	AAC	0.22	1e-05
mRNA	TNFRSF12A	GDSC1000	pan-cancer	AAC	0.22	3e-05
mRNA	YAP1	GDSC1000	pan-cancer	AAC	0.21	5e-05
mRNA	IFITM3	GDSC1000	pan-cancer	AAC	0.21	2e-06
mRNA	MYOF	GDSC1000	pan-cancer	AAC	0.21	9e-06
mRNA	TJP1	GDSC1000	pan-cancer	AAC	0.21	0.002
mRNA	HLA-E	GDSC1000	pan-cancer	AAC	0.2	2e-06

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