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RO-3306

RO-3306

Synonyms

Sources	Names Used
GDSC1000	RO-3306
PharmacoGx	RO-3306

External IDs

Database	Identifier
Smiles:	C1=CC2=C(C=CC(=C2)C=C3C(=O)N=C(S3)NCC4=CC=CS4)N=C1
Inchikey:	XOLMRFUGOINFDQ-UHFFFAOYSA-N
Pubchem:	71433937

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to RO-3306

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	HSPG2	GDSC1000	pan-cancer	AAC	0.13	0.0007
mRNA	SLC25A19	GDSC1000	pan-cancer	AAC	-0.14	0.0007
mRNA	MEX3A	GDSC1000	pan-cancer	AAC	-0.14	0.0007
mRNA	PTBP2	GDSC1000	pan-cancer	AAC	-0.12	0.0007
mRNA	MICAL2	GDSC1000	pan-cancer	AAC	0.14	0.0007
mRNA	UGT8	GDSC1000	pan-cancer	AAC	-0.13	0.0007
mRNA	NVL	GDSC1000	pan-cancer	AAC	-0.13	0.0007
mRNA	IL20RB	GDSC1000	pan-cancer	AAC	0.13	0.0007
mRNA	FGF12	GDSC1000	pan-cancer	AAC	-0.12	0.0007
mRNA	REEP6	GDSC1000	pan-cancer	AAC	0.12	0.0007

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