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BX-795

Synonyms

SourcesNames Used
GDSC1000BX-795
PharmacoGx BX-795

External IDs

DatabaseIdentifier
Smiles: C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4=CC=CS4)I
Inchikey: VAVXGGRQQJZYBL-UHFFFAOYSA-N
Pubchem: 10077147

Annotated Targets

CDK2, CHEK1, GSK3B, KDR, PDK1, PDPK1

FDA Approval Status

Not Approved
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Top molecular features associated with response to BX-795


Feature TypeStandardized
Nominal ANOVA
mRNA MVB12B GDSC1000 pan-cancer AAC 0.086 0.01
mRNA DUSP26 GDSC1000 pan-cancer AAC -0.093 0.01
mRNA ORC3 GDSC1000 pan-cancer AAC 0.084 0.01
mRNA ABI3 GDSC1000 pan-cancer AAC -0.099 0.01
mRNA DUSP2 GDSC1000 pan-cancer AAC -0.098 0.01
mRNA LIMK2 GDSC1000 pan-cancer AAC -0.095 0.01
mRNA TPRN GDSC1000 pan-cancer AAC -0.09 0.01
mRNA NFKBID GDSC1000 pan-cancer AAC -0.095 0.01
mRNA GCC1 GDSC1000 pan-cancer AAC -0.085 0.01
mRNA TMEM139 GDSC1000 pan-cancer AAC -0.11 0.01
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