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BX-795

Synonyms

SourcesNames Used
GDSC1000BX-795
PharmacoGx BX-795

External IDs

DatabaseIdentifier
Smiles: C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4=CC=CS4)I
Inchikey: VAVXGGRQQJZYBL-UHFFFAOYSA-N
Pubchem: 10077147

Annotated Targets

CDK2, CHEK1, GSK3B, KDR, PDK1, PDPK1

FDA Approval Status

Not Approved
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Top molecular features associated with response to BX-795


Feature TypeStandardized
Nominal ANOVA
mRNA NLRP3 GDSC1000 pan-cancer AAC 0.19 1e-07
mRNA ANGPTL6 GDSC1000 pan-cancer AAC -0.21 1e-07
mRNA GBGT1 GDSC1000 pan-cancer AAC 0.18 1e-07
mRNA MS4A1 GDSC1000 pan-cancer AAC -0.21 1e-07
mRNA CCL22 GDSC1000 pan-cancer AAC -0.18 1e-07
mRNA FAM20C GDSC1000 pan-cancer AAC 0.22 2e-07
mRNA FZD2 GDSC1000 pan-cancer AAC 0.2 2e-07
mRNA PIP4K2C GDSC1000 pan-cancer AAC -0.2 2e-07
mRNA ADARB1 GDSC1000 pan-cancer AAC 0.18 2e-07
mRNA BFSP2 GDSC1000 pan-cancer AAC -0.2 3e-07
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