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BX-795

Synonyms

SourcesNames Used
GDSC1000BX-795
PharmacoGx BX-795

External IDs

DatabaseIdentifier
Smiles: C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4=CC=CS4)I
Inchikey: VAVXGGRQQJZYBL-UHFFFAOYSA-N
Pubchem: 10077147

Annotated Targets

CDK2, CHEK1, GSK3B, KDR, PDK1, PDPK1

FDA Approval Status

Not Approved
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Top molecular features associated with response to BX-795


Feature TypeStandardized
Nominal ANOVA
mRNA GRB10 GDSC1000 pan-cancer AAC 0.094 0.01
mRNA ZBTB8A GDSC1000 pan-cancer AAC 0.093 0.01
mRNA RPRD1B GDSC1000 pan-cancer AAC -0.088 0.01
mRNA ZNF146 GDSC1000 pan-cancer AAC 0.09 0.01
mRNA OR10A2 GDSC1000 pan-cancer AAC -0.085 0.01
mRNA RLIM GDSC1000 pan-cancer AAC 0.087 0.01
mRNA DEFB113 GDSC1000 pan-cancer AAC 0.087 0.01
mRNA TSPAN1 GDSC1000 pan-cancer AAC -0.11 0.01
mRNA CPNE2 GDSC1000 pan-cancer AAC 0.087 0.01
mRNA PIAS2 GDSC1000 pan-cancer AAC -0.093 0.01
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