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BX-795

Synonyms

SourcesNames Used
GDSC1000BX-795
PharmacoGx BX-795

External IDs

DatabaseIdentifier
Smiles: C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4=CC=CS4)I
Inchikey: VAVXGGRQQJZYBL-UHFFFAOYSA-N
Pubchem: 10077147

Annotated Targets

CDK2, CHEK1, GSK3B, KDR, PDK1, PDPK1

FDA Approval Status

Not Approved
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Top molecular features associated with response to BX-795


Feature TypeStandardized
Nominal ANOVA
mRNA CD300LF GDSC1000 pan-cancer AAC 0.24 1e-11
mRNA MYO1F GDSC1000 pan-cancer AAC 0.26 2e-11
mRNA MRC2 GDSC1000 pan-cancer AAC 0.27 6e-11
mRNA CD80 GDSC1000 pan-cancer AAC -0.24 8e-11
mRNA MS4A6A GDSC1000 pan-cancer AAC 0.22 1e-10
mRNA KCNE5 GDSC1000 pan-cancer AAC 0.21 1e-10
mRNA ADGRA2 GDSC1000 pan-cancer AAC 0.25 2e-10
mRNA ATP8B4 GDSC1000 pan-cancer AAC 0.22 3e-10
mRNA RFX8 GDSC1000 pan-cancer AAC 0.22 6e-10
mRNA OCSTAMP GDSC1000 pan-cancer AAC 0.21 7e-10
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