Home/
Compounds/
GDC-0449

GDC-0449

Synonyms

Sources	Names Used
GDSC1000	GDC0449
FIMM	Vismodegib
PharmacoGx	GDC-0449

External IDs

Database	Identifier
Smiles:	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey:	BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem:	24776445

FDA Approval Status

Approved

Dataset Select

Download Data as CSV

Top molecular features associated with response to GDC-0449

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	REST	FIMM	pan-cancer	AAC	0.46	0.008
mRNA	DCTN3	FIMM	pan-cancer	AAC	-0.46	0.008
mRNA	NXF1	FIMM	pan-cancer	AAC	0.44	0.008
mRNA	CADPS2	FIMM	pan-cancer	AAC	-0.47	0.009
mRNA	CHD7	FIMM	pan-cancer	AAC	0.51	0.009
mRNA	SEMA4A	FIMM	pan-cancer	AAC	0.49	0.009
mRNA	SYTL2	FIMM	pan-cancer	AAC	0.44	0.01
mRNA	MAVS	FIMM	pan-cancer	AAC	0.42	0.01
mRNA	PTPRS	FIMM	pan-cancer	AAC	0.43	0.01
mRNA	METTL16	FIMM	pan-cancer	AAC	0.44	0.01

← Previous 1 2 345…199 200 Next →