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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA ATG9A GDSC1000 pan-cancer AAC -0.071 0.06
mRNA GSX1 GDSC1000 pan-cancer AAC -0.066 0.06
mRNA PRPH GDSC1000 pan-cancer AAC 0.079 0.06
mRNA SLC40A1 GDSC1000 pan-cancer AAC 0.069 0.06
mRNA FCHSD1 GDSC1000 pan-cancer AAC -0.068 0.06
mRNA HIST1H2BM GDSC1000 pan-cancer AAC 0.067 0.06
mRNA ERI1 GDSC1000 pan-cancer AAC 0.071 0.06
mRNA ETF1 GDSC1000 pan-cancer AAC 0.067 0.06
mRNA UQCRQ GDSC1000 pan-cancer AAC -0.068 0.06
mRNA GIMAP6 FIMM pan-cancer AAC 0.41 0.06
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