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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA SMAP1 FIMM pan-cancer AAC -0.33 0.06
mRNA DLG4 GDSC1000 pan-cancer AAC 0.071 0.06
mRNA RPE GDSC1000 pan-cancer AAC 0.068 0.06
mRNA TTR GDSC1000 pan-cancer AAC 0.071 0.06
mRNA BAZ1B GDSC1000 pan-cancer AAC -0.069 0.06
mRNA UBA3 GDSC1000 pan-cancer AAC 0.072 0.06
mRNA P4HA2 FIMM pan-cancer AAC -0.43 0.06
mRNA FAM47C GDSC1000 pan-cancer AAC 0.066 0.06
mRNA NEDD1 GDSC1000 pan-cancer AAC 0.068 0.06
mRNA RBP4 GDSC1000 pan-cancer AAC 0.07 0.06
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