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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA OSTN GDSC1000 pan-cancer AAC 0.066 0.06
mRNA SLC35E4 GDSC1000 pan-cancer AAC -0.068 0.06
mRNA RTP2 GDSC1000 pan-cancer AAC -0.067 0.06
mRNA MERTK FIMM pan-cancer AAC 0.33 0.06
mRNA FKBP1B GDSC1000 pan-cancer AAC 0.077 0.06
mRNA ZNF14 FIMM pan-cancer AAC 0.32 0.06
mRNA FAM174A GDSC1000 pan-cancer AAC -0.071 0.06
mRNA PRR15 GDSC1000 pan-cancer AAC -0.087 0.06
mRNA RBMS3 FIMM pan-cancer AAC -0.34 0.06
mRNA TMEM125 GDSC1000 pan-cancer AAC -0.083 0.06
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