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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA PLEKHB1 GDSC1000 pan-cancer AAC -0.069 0.06
mRNA SLC52A3 GDSC1000 pan-cancer AAC -0.082 0.06
mRNA IRX4 FIMM pan-cancer AAC 0.34 0.06
mRNA LIPT2 GDSC1000 pan-cancer AAC -0.069 0.06
mRNA RNF138 GDSC1000 pan-cancer AAC 0.079 0.06
mRNA C2orf57 GDSC1000 pan-cancer AAC -0.067 0.06
mRNA RPGR GDSC1000 pan-cancer AAC 0.07 0.06
mRNA MYO1F GDSC1000 pan-cancer AAC 0.077 0.06
mRNA CSK GDSC1000 pan-cancer AAC -0.099 0.06
mRNA CTSO FIMM pan-cancer AAC -0.32 0.06
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