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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA ARHGEF38 GDSC1000 pan-cancer AAC -0.071 0.06
mRNA APOA2 GDSC1000 pan-cancer AAC 0.074 0.06
mRNA QSOX2 GDSC1000 pan-cancer AAC -0.069 0.06
mRNA MFN2 FIMM pan-cancer AAC -0.35 0.06
mRNA HMSD GDSC1000 pan-cancer AAC 0.068 0.06
mRNA MED16 GDSC1000 pan-cancer AAC -0.069 0.06
mRNA OLFM3 GDSC1000 pan-cancer AAC 0.071 0.06
mRNA TADA2A GDSC1000 pan-cancer AAC 0.071 0.06
mRNA CXCR4 GDSC1000 pan-cancer AAC 0.091 0.06
mRNA GFM2 GDSC1000 pan-cancer AAC 0.068 0.06
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