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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA SP9 GDSC1000 pan-cancer AAC -0.069 0.05
mRNA EPYC FIMM pan-cancer AAC -0.37 0.05
mRNA N6AMT1 FIMM pan-cancer AAC -0.33 0.05
mRNA NPLOC4 GDSC1000 pan-cancer AAC -0.067 0.05
mRNA TMEM202 GDSC1000 pan-cancer AAC 0.067 0.05
mRNA APIP GDSC1000 pan-cancer AAC -0.071 0.05
mRNA CYC1 GDSC1000 pan-cancer AAC -0.068 0.05
mRNA MGAT1 GDSC1000 pan-cancer AAC -0.072 0.05
mRNA NPR2 GDSC1000 pan-cancer AAC -0.071 0.05
mRNA ANKS1B FIMM pan-cancer AAC -0.33 0.05
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