1. Home/
  2. Compounds/
  3. GDC-0449

GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA MEF2D GDSC1000 pan-cancer AAC -0.08 0.05
mRNA DES GDSC1000 pan-cancer AAC 0.069 0.05
mRNA SEMA3F GDSC1000 pan-cancer AAC -0.074 0.05
mRNA KCNJ5 FIMM pan-cancer AAC -0.33 0.05
mRNA TCEANC GDSC1000 pan-cancer AAC -0.072 0.05
mRNA PAQR6 GDSC1000 pan-cancer AAC -0.072 0.05
mRNA ROBO1 FIMM pan-cancer AAC -0.33 0.05
mRNA PMM2 GDSC1000 pan-cancer AAC -0.069 0.05
mRNA CACNA1I GDSC1000 pan-cancer AAC -0.071 0.05
mRNA PAK1IP1 GDSC1000 pan-cancer AAC 0.068 0.05
Download CSV