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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA TNS1 GDSC1000 pan-cancer AAC -0.071 0.05
mRNA BHLHE23 GDSC1000 pan-cancer AAC 0.069 0.05
mRNA C1orf123 GDSC1000 pan-cancer AAC 0.072 0.05
mRNA SIPA1L3 GDSC1000 pan-cancer AAC -0.069 0.05
mRNA LCE3A GDSC1000 pan-cancer AAC -0.068 0.05
mRNA GEMIN6 GDSC1000 pan-cancer AAC 0.068 0.05
mRNA C9orf85 GDSC1000 pan-cancer AAC 0.069 0.05
mRNA TANGO6 GDSC1000 pan-cancer AAC 0.069 0.05
mRNA HERC5 GDSC1000 pan-cancer AAC 0.068 0.05
mRNA ZNF235 GDSC1000 pan-cancer AAC 0.071 0.05
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