1. Home/
  2. Compounds/
  3. GDC-0449

GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA PLCXD1 FIMM pan-cancer AAC 0.39 0.05
mRNA NTF4 GDSC1000 pan-cancer AAC 0.083 0.05
mRNA POU2F2 FIMM pan-cancer AAC 0.32 0.05
mRNA LRRC24 GDSC1000 pan-cancer AAC -0.072 0.05
mRNA C2orf54 GDSC1000 pan-cancer AAC -0.071 0.05
mRNA MRPS18C FIMM pan-cancer AAC 0.37 0.05
mRNA ADH4 GDSC1000 pan-cancer AAC 0.072 0.05
mRNA ALG3 GDSC1000 pan-cancer AAC -0.069 0.05
mRNA IL11RA FIMM pan-cancer AAC -0.33 0.05
mRNA WFS1 GDSC1000 pan-cancer AAC -0.074 0.05
Download CSV