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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA SCN7A FIMM pan-cancer AAC 0.33 0.05
mRNA NMRK2 GDSC1000 pan-cancer AAC -0.07 0.05
mRNA PTK2B FIMM pan-cancer AAC 0.58 0.05
mRNA TMEM63A GDSC1000 pan-cancer AAC -0.077 0.05
mRNA PIN1 FIMM pan-cancer AAC -0.33 0.05
mRNA PIGQ GDSC1000 pan-cancer AAC -0.068 0.05
mRNA NR1I2 FIMM pan-cancer AAC -0.4 0.05
mRNA EBNA1BP2 GDSC1000 pan-cancer AAC 0.068 0.05
mRNA APC FIMM pan-cancer AAC 0.38 0.05
mRNA VEGFB FIMM pan-cancer AAC -0.35 0.05
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