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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF821 GDSC1000 pan-cancer AAC -0.071 0.05
mRNA MIGA2 GDSC1000 pan-cancer AAC -0.074 0.05
mRNA BORCS8 GDSC1000 pan-cancer AAC -0.068 0.05
mRNA ST8SIA6 GDSC1000 pan-cancer AAC 0.068 0.05
mRNA GDNF GDSC1000 pan-cancer AAC -0.068 0.05
mRNA SREK1IP1 FIMM pan-cancer AAC 0.4 0.05
mRNA PRDM7 GDSC1000 pan-cancer AAC -0.082 0.05
mRNA NCF4 GDSC1000 pan-cancer AAC 0.11 0.05
mRNA LETMD1 FIMM pan-cancer AAC 0.35 0.05
mRNA ATF7IP FIMM pan-cancer AAC 0.32 0.05
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