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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA ODF3B GDSC1000 pan-cancer AAC 0.072 0.05
mRNA RIC1 GDSC1000 pan-cancer AAC 0.083 0.05
mRNA MYO1B GDSC1000 pan-cancer AAC 0.096 0.05
mRNA RAB3D GDSC1000 pan-cancer AAC 0.07 0.05
mRNA LRRC6 GDSC1000 pan-cancer AAC 0.072 0.05
mRNA EIF1AD GDSC1000 pan-cancer AAC -0.069 0.05
mRNA DIP2C GDSC1000 pan-cancer AAC -0.077 0.05
mRNA TRIM17 FIMM pan-cancer AAC 0.32 0.05
mRNA UROC1 GDSC1000 pan-cancer AAC -0.069 0.05
mRNA ANP32A GDSC1000 pan-cancer AAC 0.081 0.05
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