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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA C1orf162 GDSC1000 pan-cancer AAC 0.074 0.05
mRNA PPP1R1B GDSC1000 pan-cancer AAC -0.078 0.05
mRNA H2AFY GDSC1000 pan-cancer AAC -0.074 0.05
mRNA PLOD2 FIMM pan-cancer AAC -0.4 0.05
mRNA ST18 FIMM pan-cancer AAC 0.36 0.05
mRNA TSLP GDSC1000 pan-cancer AAC 0.07 0.05
mRNA SLC6A12 GDSC1000 pan-cancer AAC 0.069 0.05
mRNA RPLP1 GDSC1000 pan-cancer AAC 0.072 0.05
mRNA ZDHHC14 GDSC1000 pan-cancer AAC 0.069 0.05
mRNA ZSWIM7 GDSC1000 pan-cancer AAC 0.068 0.05
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