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GDC-0449

Synonyms

SourcesNames Used
GDSC1000GDC0449
FIMMVismodegib
PharmacoGx GDC-0449

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Inchikey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
Pubchem: 24776445

FDA Approval Status

Approved
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Top molecular features associated with response to GDC-0449


Feature TypeStandardized
Nominal ANOVA
mRNA KBTBD8 GDSC1000 pan-cancer AAC 0.094 0.05
mRNA KLRD1 FIMM pan-cancer AAC -0.33 0.05
mRNA CLCN5 GDSC1000 pan-cancer AAC 0.076 0.05
mRNA DISC1 GDSC1000 pan-cancer AAC 0.071 0.05
mRNA BTN3A3 FIMM pan-cancer AAC -0.34 0.05
mRNA ZFYVE28 GDSC1000 pan-cancer AAC -0.07 0.05
mRNA SLC26A11 GDSC1000 pan-cancer AAC -0.08 0.05
mRNA CPB1 FIMM pan-cancer AAC -0.33 0.05
mRNA SLC5A1 GDSC1000 pan-cancer AAC -0.079 0.05
mRNA PTMS GDSC1000 pan-cancer AAC -0.089 0.05
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